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Antimicrobial resistance.

A growing threat to modern medicine — and one of the top ten global public health threats facing humanity.

~2 min
One child under five dies nearly every two minutes because of AMR
~136M
Healthcare-associated antibiotic-resistant infections each year, 2010–2020
10M
Projected annual deaths from AMR by 2050
50%+
Of AMR-associated deaths are due to multidrug-resistant Gram-negative pathogens
A global threat

Imagine losing one of the world's most powerful tools in healthcare.

Antimicrobial resistance (AMR) is one of the top ten global public health threats facing humanity. It occurs when bacteria and other microbes adapt and become resistant to antibiotics — a foundation of modern healthcare.

As resistance grows, antibiotics become less effective, threatening to unwind nearly a century of medical progress across a wide range of treatments, from complex surgeries and cancer chemotherapy to organ transplantation and neonatal intensive care.

Escherichia coli bacteria
Amplifying the burden

Not a distant threat — a pressing reality.

AMR is not a distant, long-term, and abstract threat. It is a pressing reality that should be integrated into public health, humanitarian, and security response. Hover or tap a card to learn more.

Unmet medical need

The pipeline is not keeping pace.

Continuous anti-infective innovation is imperative to keep pace with evolving pathogens and improve outcomes for patients facing serious infections. Yet the antibiotic development pipeline remains limited, with dwindling treatment options and too few truly novel approaches.

Many candidates are derivatives of existing antibiotic classes, leaving them vulnerable to the same resistance mechanisms and shortening their useful clinical life. As a result, new classes of antibiotics and differentiated anti-infective therapies are urgently needed to address difficult-to-treat infections.

A selection of antibiotic capsules, tablets, and an injectable vial
Fedora's response

Advancing a novel antibiotic pipeline against the highest-priority resistant pathogens.

Fedora is advancing a novel antibiotic pipeline, including a first-in-class candidate, addressing the world's highest-priority resistant pathogens.

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